AnteAGE MD® Biosome™ Serum

Concentrated Bone Marrow Stem Cytokine & Recombinant Growth Factor Treatment

The AnteAGE MD® Biosome™ Serum is a medical-grade, aqueous corrective treatment engineered to initiate cellular repair, reverse signs of photoaging, calm chronic micro-inflammation, and restore youthful skin architecture. Formulated with a physiological concentration of Human Bone Marrow Stem Cytokines wrapped in lipid Biosome™ nano-carriers, this restorative serum is fortified with recombinant growth factors TGF-β3 and IGF-1, signal peptides, and potent antioxidants.

Designed as the foundational first step of the AnteAGE MD® System, its water-based matrix penetrates rapidly into the skin to communicate directly with cell receptors. Ideal for all skin types—including sensitive, reactive, post-procedure, and menopausal skin experiencing estrogen-loss thinning and collagen depletion—it reduces fine lines, refines texture, and restores structural elasticity from within.

Clinical Note: AnteAGE MD® Biosome™ Serum is designed as Step 1 of the AnteAGE MD® System. For maximum rejuvenation, layer AnteAGE MD® Biosome™ Accelerator immediately afterward to seal in cytokine signaling and deliver lipid-soluble antioxidants.

Key Benefits

• Concentrated Cellular Regeneration: Delivers bone marrow-derived Stem Cytokines™ to trigger deep tissue repair and boost natural collagen synthesis.

• Targeted Recombinant Growth Factors: Fortified with TGF-β3 (anti-inflammatory remodeling factor) and IGF-1 (insulin-like growth factor) to accelerate skin recovery and density.

• Enhanced Biosome™ Delivery: Nanolipid carriers encapsulate bioactive proteins for optimal dermal penetration and target-cell signaling.

• Reduces Fine Lines & Wrinkles: Signal peptides and growth factors smooth expression lines, improve elasticity, and firm sagging tissue.

• Anti-Inflammatory Barrier Support: Suppresses inflammatory pathways to calm facial redness, surface reactivity, and post-procedure stress.

• Weightless Aqueous Absorption: Ultra-fast absorbing liquid matrix leaves zero residue, prepping skin for downstream active treatments.

Targeted Skin Types & Concerns

• Best For: All skin types, including Dry, Normal, Combination, Oily, Mature, Sensitive, Reactive, and Post-Procedure complexions.

• Skin Concerns: Fine lines, deep wrinkles, loss of firmness, structural elasticity loss, compromised skin barriers, facial redness, post-treatment recovery, and menopausal skin thinning.

Sensory Profile

• What You'll See: A visibly firmer, plumper, and more youthful complexion with softened lines, even tone, and a vibrant, healthy glow over time.

• What You'll Feel: A light, silky aqueous fluid that absorbs within seconds, leaving tissue feeling refreshed, balanced, and hydrated.

Key Active Ingredients & Science

• Human Bone Marrow Stem Cell Conditioned Media (Stem Cytokines™): Physiologically balanced signaling proteins derived from human bone marrow stem cells that instruct skin cells to heal, repair, and produce structural proteins.

• TGF-β3 (Transforming Growth Factor Beta-3): A key anti-inflammatory cytokine that promotes scarless skin healing and organizes collagen fiber formation.

• IGF-1 (Insulin-like Growth Factor 1): Stimulates cell proliferation, tissue remodeling, and epidermal matrix density.

• Proprietary Biosome™ Nanolipid Carriers: Advanced lipid vesicles that shield delicate protein structures and facilitate deep cutaneous absorption.

• Niacinamide (Vitamin B3) & Peptides: Calms surface micro-inflammation, supports barrier lipid synthesis, and works synergistically to relax fine lines.

• High-Purity Hyaluronic Acid: Delivers immediate surface and sub-surface moisture binding to plump dehydration lines.

How to Use

AM and/or PM | Foundational Corrective Step (Step 2: Correct)

After cleansing, dispense 1 to 2 pumps of AnteAGE MD® Biosome™ Serum onto clean fingertips. Massage evenly over clean, dry skin on the face, neck, and décolleté using gentle press-and-glide motions. Allow 30 to 60 seconds for full absorption before applying AnteAGE MD® Biosome™ Accelerator or your recommended moisturizer.

Recommended Protocol:

• System Layering: Apply first on clean skin to ensure uninterrupted protein-receptor binding before applying lipid-based creams or oils.

• Post-Procedure Protocol: Safe and highly recommended for use immediately following microneedling, laser resurfacing, and chemical peels to accelerate healing and reduce downtime.

• Daily Application: Use twice daily (morning and evening) for optimal cell-signaling results.

AM: Always complete daytime regimens with broad-spectrum SPF 30 or higher (such as Mesoprotech Light Water Veil or Mineral Matt Fluid).

Amare Clinical Tip: Bone marrow stem cytokines are biologically superior for adult skin repair because they are inherently anti-inflammatory (unlike fat-derived stem cells, which carry pro-inflammatory markers). In skin of color (Fitzpatrick IV–VI) or reactive mature skin, suppressing inflammation during cellular turnover is essential to prevent post-inflammatory hyperpigmentation (PIH).

Important to Know

• Physiological Growth Factor Formula: Contains human bone marrow-derived proteins engineered for high biocompatibility.

• Fragrance & Oil Free: Formulated without heavy oils, artificial dyes, or synthetic fragrances, making it suitable for hypersensitive and compromised skin.

• Post-Procedure Safe: Excellent soothing serum following in-office clinical treatments.

• Daily Sunscreen Essential: Protect freshly repaired collagen and newly renewed skin with daily broad-spectrum SPF 30+.

Frequently Asked Questions

Why are Bone Marrow Stem Cells preferred over other stem cell sources?

Human bone marrow stem cells act as the body's natural command center for tissue repair. Their conditioned media contains a high concentration of anti-inflammatory cytokines that instruct aged or damaged skin cells to rebuild without triggering inflammatory stress or irritation.

Can I use AnteAGE MD® Biosome™ Serum while using active Vitamin A or Retinoids?

Yes. Applying AnteAGE MD® Biosome™ Serum prior to your evening retinoid (such as Vivant Exfol-A or Retinyl Propionate) cushions the skin, reduces retinoid-induced redness, and accelerates epidermal recovery.

Is AnteAGE MD® Biosome™ Serum suitable for menopausal skin concerns?

Yes. Estrogen loss during perimenopause and menopause leads to a dramatic decrease in skin thickness and collagen density. The stem cytokines and recombinant growth factors in this serum signal dermal fibroblasts to rebuild matrix support and improve structural firmness.

Why Buy AnteAGE From Amare Aesthetics?

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