{"product_id":"mesoestetic-cosmelan-2","title":"Cosmelan 2","description":"\u003ch1 data-path-to-node=\"11\"\u003eMesoestetic Cosmelan 2\u003c\/h1\u003e\n\u003ch3 data-path-to-node=\"12\"\u003eIntensive Home Depigmenting \u0026amp; Melanin-Regulating Treatment Cream\u003c\/h3\u003e\n\u003cp data-path-to-node=\"13\"\u003e\u003cspan\u003eThe \u003c\/span\u003e\u003cb data-path-to-node=\"13\" data-index-in-node=\"4\"\u003eMesoestetic Cosmelan 2\u003c\/b\u003e\u003cspan\u003e is an intensive home-care depigmenting maintenance cream engineered to correct stubborn hyperpigmentation,\u003c\/span\u003e\u003cspan\u003e melasma,\u003c\/span\u003e\u003cspan\u003e and dark spots while regulating continuous melanin synthesis.\u003c\/span\u003e\u003cspan\u003e Suitable for all skin phototypes (Fitzpatrick 1–6),\u003c\/span\u003e\u003cspan\u003e this advanced formula treats active surface discoloration and inhibits the biological pathways that trigger new dark spots.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"14\"\u003e\u003cspan\u003eDesigned specifically as essential home follow-up care for professional in-office depigmenting treatments (such as the Cosmelan 1 mask),\u003c\/span\u003e\u003cspan\u003e Cosmelan 2 keeps melanocytes under control.\u003c\/span\u003e\u003cspan\u003e Whether managing melasma,\u003c\/span\u003e\u003cspan\u003e sun spots,\u003c\/span\u003e\u003cspan\u003e post-inflammatory hyperpigmentation (PIH),\u003c\/span\u003e\u003cspan\u003e or hormonal pigment fluctuations—including those intensified during perimenopause and menopause—this high-potency cream delivers a continuous,\u003c\/span\u003e\u003cspan\u003e multi-target approach for a uniform,\u003c\/span\u003e\u003cspan\u003e luminous complexion.\u003c\/span\u003e\u003c\/p\u003e\n\u003cblockquote data-path-to-node=\"15\" class=\"\"\u003e\n\u003cp data-path-to-node=\"15,0\"\u003e\u003cb data-path-to-node=\"15,0\" data-index-in-node=\"0\"\u003eClinical Note:\u003c\/b\u003e \u003ci data-path-to-node=\"15,0\" data-index-in-node=\"15\"\u003eThis professional-grade home treatment requires a prior consultation for approval. Recommended exclusively for in-office treatment follow-up or structured practitioner-guided maintenance regimens.\u003c\/i\u003e\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003ch3 data-path-to-node=\"16\"\u003eKey Benefits\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli data-path-to-node=\"17,0,0\"\u003e\n\u003cb data-path-to-node=\"17,0,0\" data-index-in-node=\"0\"\u003eIntensive Pigment Correction:\u003c\/b\u003e\u003cspan\u003e Accelerates the fading of stubborn melasma,\u003c\/span\u003e\u003cspan\u003e sun spots,\u003c\/span\u003e\u003cspan\u003e senile lentigines,\u003c\/span\u003e\u003cspan\u003e and post-acne dark marks.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-path-to-node=\"17,1,0\"\u003e\n\u003cb data-path-to-node=\"17,1,0\" data-index-in-node=\"0\"\u003eRegulates Melanin Production:\u003c\/b\u003e\u003cspan\u003e Blocks key steps in the melanogenesis cascade to prevent the reappearance of previously treated dark spots.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-path-to-node=\"17,2,0\"\u003e\n\u003cb data-path-to-node=\"17,2,0\" data-index-in-node=\"0\"\u003ePrevents New Dark Spots:\u003c\/b\u003e\u003cspan\u003e Keeps tyrosinase enzyme activity suppressed to halt future hyperpigmentation before it reaches the skin surface.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-path-to-node=\"17,3,0\" id=\"p-rc_8748588757ceb051-29\"\u003e\n\u003cb data-path-to-node=\"17,3,0\" data-index-in-node=\"0\"\u003eAccelerates Surface Resurfacing:\u003c\/b\u003e\u003cspan class=\"\"\u003e \u003c\/span\u003e\u003cspan class=\"citation-234 citation-end-234\"\u003ePromotes rapid cellular turnover to lift existing pigmented cells and smooth skin texture.\u003csup class=\"superscript\" data-turn-source-index=\"1\"\u003e\u003c!----\u003e\u003c\/sup\u003e\u003c\/span\u003e \u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\n\u003c\/li\u003e\n\u003cli data-path-to-node=\"17,4,0\"\u003e\n\u003cb data-path-to-node=\"17,4,0\" data-index-in-node=\"0\"\u003eUniversal Phototype Efficacy:\u003c\/b\u003e\u003cspan\u003e High clinical safety and efficacy across all skin tones,\u003c\/span\u003e\u003cspan\u003e including deeper Fitzpatrick phototypes prone to post-inflammatory hyperpigmentation.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"18\"\u003eTargeted Skin Types \u0026amp; Concerns\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli data-path-to-node=\"19,0,0\"\u003e\n\u003cb data-path-to-node=\"19,0,0\" data-index-in-node=\"0\"\u003eSkin Types:\u003c\/b\u003e\u003cspan\u003e All skin types and phototypes (Fitzpatrick I–VI).\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-path-to-node=\"19,1,0\"\u003e\n\u003cb data-path-to-node=\"19,1,0\" data-index-in-node=\"0\"\u003eSkin Concerns:\u003c\/b\u003e\u003cspan\u003e Melasma,\u003c\/span\u003e\u003cspan\u003e chloasma,\u003c\/span\u003e\u003cspan\u003e age spots,\u003c\/span\u003e\u003cspan\u003e post-inflammatory hyperpigmentation (PIH),\u003c\/span\u003e\u003cspan\u003e contraceptive-induced pigmentation,\u003c\/span\u003e\u003cspan\u003e uneven skin tone,\u003c\/span\u003e\u003cspan\u003e and menopausal discoloration.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"20\"\u003eSensory Profile\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli data-path-to-node=\"21,0,0\"\u003e\n\u003cb data-path-to-node=\"21,0,0\" data-index-in-node=\"0\"\u003eWhat You'll See:\u003c\/b\u003e\u003cspan\u003e A progressively clearer,\u003c\/span\u003e\u003cspan\u003e more even-toned complexion with visibly faded dark spots and refined skin texture.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-path-to-node=\"21,1,0\"\u003e\n\u003cb data-path-to-node=\"21,1,0\" data-index-in-node=\"0\"\u003eWhat You'll Feel:\u003c\/b\u003e\u003cspan\u003e A rich,\u003c\/span\u003e\u003cspan\u003e active cream finish; temporary tightness,\u003c\/span\u003e\u003cspan\u003e mild peeling,\u003c\/span\u003e\u003cspan\u003e or localized warmth may be felt during early skin acclimation.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"22\"\u003eKey Active Ingredients \u0026amp; Science\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli data-path-to-node=\"23,0,0\"\u003e\n\u003cb data-path-to-node=\"23,0,0\" data-index-in-node=\"0\"\u003eAzelaic Acid \u0026amp; Kojic Acid:\u003c\/b\u003e\u003cspan\u003e High-performance tyrosinase inhibitors that block melanin synthesis at the cellular level and calm inflammatory pigment signals.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-path-to-node=\"23,1,0\"\u003e\n\u003cb data-path-to-node=\"23,1,0\" data-index-in-node=\"0\"\u003eNiacinamide (Vitamin B3):\u003c\/b\u003e\u003cspan\u003e Blocks melanosome transfer from melanocytes to surface skin cells while strengthening the lipid barrier and calming redness.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-path-to-node=\"23,2,0\"\u003e\n\u003cb data-path-to-node=\"23,2,0\" data-index-in-node=\"0\"\u003eRetinol \u0026amp; Retinyl Palmitate:\u003c\/b\u003e\u003cspan\u003e Accelerate epidermal cell turnover,\u003c\/span\u003e\u003cspan\u003e forcing pigmented cells to shed faster and boosting collagen synthesis.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-path-to-node=\"23,3,0\"\u003e\n\u003cb data-path-to-node=\"23,3,0\" data-index-in-node=\"0\"\u003ePhytic Acid \u0026amp; Salicylic Acid:\u003c\/b\u003e\u003cspan\u003e Synergistic exfoliants that dissolve intercellular bonds,\u003c\/span\u003e\u003cspan\u003e clear surface buildup,\u003c\/span\u003e\u003cspan\u003e and improve active ingredient delivery.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-path-to-node=\"23,4,0\" id=\"p-rc_8748588757ceb051-30\"\u003e\n\u003cb data-path-to-node=\"23,4,0\" data-index-in-node=\"0\"\u003eAscorbic Acid (Vitamin C) \u0026amp; Alpha-Arbutin:\u003c\/b\u003e\u003cspan class=\"\"\u003e \u003c\/span\u003e\u003cspan class=\"citation-233 citation-end-233\"\u003eProvide antioxidant protection while brightening existing discoloration and unifying overall skin tone.\u003csup class=\"superscript\" data-turn-source-index=\"2\"\u003e\u003c!----\u003e\u003c\/sup\u003e\u003c\/span\u003e \u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"27\"\u003eHow to Use\u003c\/h3\u003e\n\u003cp data-path-to-node=\"28\"\u003e\u003cb data-path-to-node=\"28\" data-index-in-node=\"0\"\u003eAM \u0026amp; PM | Daily (Under Professional Guidance)\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"29\"\u003e\u003cspan\u003eApply a pea-sized amount to clean,\u003c\/span\u003e\u003cspan\u003e dry skin on the face,\u003c\/span\u003e\u003cspan\u003e avoiding the delicate eye area,\u003c\/span\u003e\u003cspan\u003e nostrils,\u003c\/span\u003e\u003cspan\u003e and lips.\u003c\/span\u003e\u003cspan\u003e Gently massage using upward circular motions until fully absorbed.\u003c\/span\u003e\u003cspan\u003e Follow with a barrier-restoring,\u003c\/span\u003e\u003cspan\u003e soothing moisturizer (such as Mesoestetic Melan Recovery) and daily high-protection sunscreen.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"30\"\u003e\u003cb data-path-to-node=\"30\" data-index-in-node=\"0\"\u003eRecommended Maintenance Protocol:\u003c\/b\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli data-path-to-node=\"31,0,0\"\u003e\n\u003cb data-path-to-node=\"31,0,0\" data-index-in-node=\"0\"\u003eMonths 1–2 (Post-Peel Maintenance):\u003c\/b\u003e\u003cspan\u003e Apply 3 times daily (Morning,\u003c\/span\u003e\u003cspan\u003e Midday,\u003c\/span\u003e\u003cspan\u003e Evening) or as specifically prescribed by your aesthetic provider.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-path-to-node=\"31,1,0\"\u003e\n\u003cb data-path-to-node=\"31,1,0\" data-index-in-node=\"0\"\u003eMonths 3–4:\u003c\/b\u003e\u003cspan\u003e Reduce application to 2 times daily (Morning and Evening).\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-path-to-node=\"31,2,0\"\u003e\n\u003cb data-path-to-node=\"31,2,0\" data-index-in-node=\"0\"\u003eMonths 5–6 and Beyond:\u003c\/b\u003e\u003cspan\u003e Apply 1 time daily (Evening) to maintain long-term pigment suppression.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-path-to-node=\"32\"\u003e\u003cb data-path-to-node=\"32\" data-index-in-node=\"0\"\u003eAM:\u003c\/b\u003e\u003cspan\u003e Daily broad-spectrum SPF 50+ (such as Mesoprotech Melan 130 Pigment Control) is strictly mandatory.\u003c\/span\u003e\u003cspan\u003e Reapply throughout the day.\u003c\/span\u003e\u003cspan\u003e For patients managing melasma or persistent hyperpigmentation,\u003c\/span\u003e\u003cspan\u003e broad-spectrum tinted sunscreen containing iron oxides provides crucial visible-light protection.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"33\"\u003e\u003cb data-path-to-node=\"33\" data-index-in-node=\"0\"\u003eAmare Clinical Tip:\u003c\/b\u003e\u003cspan\u003e Skin peeling,\u003c\/span\u003e\u003cspan\u003e mild redness,\u003c\/span\u003e\u003cspan\u003e and temporary tightness are normal expected reactions during the first 2 to 4 weeks of Cosmelan 2 treatment.\u003c\/span\u003e\u003cspan\u003e Never pick or pull flaking skin.\u003c\/span\u003e\u003cspan\u003e Always prioritize barrier restoration with soothing postbiotics and broad-spectrum SPF to prevent secondary post-inflammatory hyperpigmentation (PIH).\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 data-path-to-node=\"34\"\u003eImportant to Know\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli data-path-to-node=\"35,0,0\"\u003e\n\u003cb data-path-to-node=\"35,0,0\" data-index-in-node=\"0\"\u003eConsultation Required:\u003c\/b\u003e\u003cspan\u003e This product contains high-potency active depigmenting agents and requires practitioner consultation before purchase and use.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-path-to-node=\"35,1,0\"\u003e\n\u003cb data-path-to-node=\"35,1,0\" data-index-in-node=\"0\"\u003eAcclimation Phase Expected:\u003c\/b\u003e\u003cspan\u003e Mild-to-moderate peeling,\u003c\/span\u003e\u003cspan\u003e redness,\u003c\/span\u003e\u003cspan\u003e tingling,\u003c\/span\u003e\u003cspan\u003e and skin dryness are normal during the initial weeks of application.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-path-to-node=\"35,2,0\"\u003e\n\u003cb data-path-to-node=\"35,2,0\" data-index-in-node=\"0\"\u003eAvoid Active Combinations:\u003c\/b\u003e\u003cspan\u003e Do not combine with external AHA\/BHA exfoliants,\u003c\/span\u003e\u003cspan\u003e prescription tretinoin,\u003c\/span\u003e\u003cspan\u003e or benzoyl peroxide while using Cosmelan 2 unless specifically directed by your provider.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-path-to-node=\"35,3,0\"\u003e\n\u003cb data-path-to-node=\"35,3,0\" data-index-in-node=\"0\"\u003eStrict Sun Avoidance:\u003c\/b\u003e\u003cspan\u003e Pigmentation will return if skin is exposed to direct sunlight without adequate high-factor SPF protection.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3 data-path-to-node=\"36\"\u003eFrequently Asked Questions\u003c\/h3\u003e\n\u003cp data-path-to-node=\"37\"\u003e\u003cb data-path-to-node=\"37\" data-index-in-node=\"0\"\u003eWhy is a consultation required before buying Mesoestetic Cosmelan 2?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"38\" id=\"p-rc_8748588757ceb051-32\"\u003e\u003cspan class=\"citation-226 citation-end-226\"\u003eCosmelan 2 contains medical-grade active ingredients (including retinoids, kojic acid, and azelaic acid) designed to follow in-office treatments.\u003csup class=\"superscript\" data-turn-source-index=\"9\"\u003e\u003c!----\u003e\u003c\/sup\u003e\u003c\/span\u003e\u003cspan\u003e A consultation ensures your skin barrier is appropriate for active depigmentation and prevents adverse reactions.\u003c\/span\u003e \u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"39\"\u003e\u003cb data-path-to-node=\"39\" data-index-in-node=\"0\"\u003eCan Cosmelan 2 be used for menopausal melasma and hormonal hyperpigmentation?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"40\" id=\"p-rc_8748588757ceb051-33\"\u003e\u003cspan\u003eYes.\u003c\/span\u003e\u003cspan\u003e Estrogen fluctuations during perimenopause and menopause frequently trigger or worsen melasma.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003e\u003cspan class=\"citation-225 citation-end-225\"\u003eCosmelan 2 inhibits tyrosinase activity to keep hormonal pigment production suppressed while promoting cell renewal.\u003csup class=\"superscript\" data-turn-source-index=\"10\"\u003e\u003c!----\u003e\u003c\/sup\u003e\u003c\/span\u003e \u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c!----\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"41\"\u003e\u003cb data-path-to-node=\"41\" data-index-in-node=\"0\"\u003eWhat should I do if my skin becomes excessively red or dry while using Cosmelan 2?\u003c\/b\u003e\u003c\/p\u003e\n\u003cp data-path-to-node=\"42\"\u003e\u003cspan\u003eTemporary dryness and flaking are normal.\u003c\/span\u003e\u003cspan\u003e If irritation becomes uncomfortable,\u003c\/span\u003e\u003cspan\u003e temporarily pause application for 1–2 days,\u003c\/span\u003e\u003cspan\u003e increase your application of barrier-repair cream (such as Mesoestetic Melan Recovery),\u003c\/span\u003e\u003cspan\u003e and consult your Amare Aesthetics practitioner before resuming.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 data-path-to-node=\"43\"\u003eWhy Buy Mesoestetic From Amare Aesthetics?\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli data-path-to-node=\"44,0,0\"\u003e\n\u003cstrong\u003e100% Guaranteed Authentic:\u003c\/strong\u003e\u003cspan\u003e\u003cstrong\u003e \u003c\/strong\u003eAuthorized mesoestetic stockist.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003cli data-path-to-node=\"44,1,0\" style=\"font-weight: bold;\"\u003e\u003cstrong\u003eFresh Inventory and Fast \u0026amp; Insured Shipping\u003c\/strong\u003e\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Mesoestetic","offers":[{"title":"Default Title","offer_id":40516928077868,"sku":"","price":260.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0365\/8619\/2940\/products\/Cosmelan-2_mesoestetic.jpg?v=1793304636","url":"https:\/\/amareaesthetics.com\/products\/mesoestetic-cosmelan-2","provider":"amare aesthetics","version":"1.0","type":"link"}